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1004-150 - Cytokines CellGro IL-6 (Interleukin-6) GMP grade
Product details
Product number 1004-150
Product name Cytokines CellGro IL-6 (Interleukin-6) GMP grade
Quantity 150µg / 1 vial
Supplier gentaur

CellGenix™ GMP Cytokines for ex vivo expansion

of human hematopoietic progenitor cells

CellGenix™ Cytokines combine a

maximum of quality and safety

with excellent performance due

to state-of-the-art production,

quality control and documentation.

A batch-specific certificate

of analysis is sent with each

cytokine. CellGenix™ Cytokines

are components of our

CellGenix™ Kit-System.

CGX-DO/M-048a

High Quality

GMP Cytokines

CellGenix™ Cytokines are manufactured

under GMP conditions.

Areas of Application

• Ex vivo expansion of

cord blood stem cells

• Ex vivo gene therapy protocols

• Ex vivo expansion of megakaryocytic

progenitor cells

Quality Controls include

• specific activity

• sterility

• purity

• endotoxin-test

To ensure consistency of quality,

results must meet our pre-defined

specifications.

Full Range of

GMP Cytokines

Several human recombinant cytokines

are available for ex vivo expansion

of human hematopoietic progenitor

cells and for the generation

of dendritic cells, respectively (please

see our special flyer „CellGenix™

GMP Cytokines for DC Generation“).

CellGenix™ SCF . . . . . . . . . . . . . . . . . . . . . . . . . . . 1001

rec. human Stem Cell Factor

CellGenix™ FLT3-ligand . . . . . . . . . . . . . . . . . . . . 1005

rec. human FLT3-ligand

CellGenix™ TPO . . . . . . . . . . . . . . . . . . . . . . . . . . . 1007

rec. human Thrombopoietin

CellGenix™ IL-3. . . . . . . . . . . . . . . . . . . . . . . . . . . 1002

rec. human Interleukin-3

CellGenix™ IL-6. . . . . . . . . . . . . . . . . . . . . . . . . . . 1004

rec. human Interleukin-6

CellGenix™ Cytokine . . . . . . . . . . . . . . . . . . . Order No.

50µg

at -20°C to -80°C

carrier-free

Certificate of Analysis

CellGenix™ SCGM

is a serum-free medium developed

for optimal culture and expansion

of hematopoietic stem and progenitor

cells, T-cells or NK-cells.

Intended Use:

• ex vivo cell culture

• for research use only

Reconstitution:

Reconstitute in sterile PBS

or sterile water to a final

concentration of 100 µg/ml.

Handling Instructions for CellGenix™ GMP Cytokines

Dilution:

Recommended in CellGenix™

SCGM. For dilution with PBS or

base medium carrier protein

(0.1-1% albumin or 1-10%

appropriate serum) has to be

included. Failure to dilute product

according to these instructions

may result in loss of activity.

Storage and Stability:

Store material at –20°C to –80°C.

Store diluted material at –20°C

to –80°C. Avoid multiple freeze /

thaw cycles.

CellGenix™ SCGM

is produced according to GMP

and available in bottles and bags.

QC Documentation:

Certificate of Analysis

 

 

 

CellGro® GMP Cytokines for DC Generation

CellGro® Cytokines combine a

maximum of quality and safety

with excellent performance due

to state-of-the-art production,

quality control and documentation.

A batch-specific certificate

of analysis is sent with each

cytokine. CellGro® Cytokines

are components of our CellGro®

DC Kit-System.

The choice of your cytokine cocktail

influences the results of your

ex vivo cell culture dramatically.

CGX-DO/M-038b

High Quality

GMP Cytokines

CellGro® Cytokines are manufactured

under GMP conditions.

Quality Controls include

• specific activity

• sterility

• purity

• endotoxin-test

To ensure consistency of quality,

results must meet our pre-defined

specifications.

Full Range of

GMP Cytokines

Several human recombinant

cytokines are available for the

generation of dendritic cells.

Intended use

• ex vivo cell culture

• for research use only

CellGro® GM-CSF. . . . . . . . . . . . . . . . . . . . . . . . 1012

rec. human Granulocyte-Macrophage

Colony Stimulating Factor

CellGro® IL-4 . . . . . . . . . . . . . . . . . . . . . . . . . . . 1003

rec. human Interleukin-4

CellGro® TNF-alpha . . . . . . . . . . . . . . . . . . . . . . 1006

rec. human Tumor Necrosis Factor-alpha

CellGro® IL-6 . . . . . . . . . . . . . . . . . . . . . . . . . . . 1004

rec. human Interleukin-6

CellGro® IL-1 beta . . . . . . . . . . . . . . . . . . . . . . . 1011

rec. human Interleukin-1 beta

CellGro® Cytokines . . . . . . . . . . . . . . . . . . . Order No.

50µg

at -20°C to -80°C

carrier-free

Certificate of Analysis

Reconstitution:

Reconstitute in sterile PBS to a

final concentration of 100 µg/ml.

Dilution:

Recommended in CellGro® DC

Medium. For dilution with PBS

or base medium carrier protein

(0.1–1% albumin or 1–10%

appropriate serum) has to be

included. Failure to dilute product

according to these instructions

may result in loss of activity.

Storage and Stability:

Store material at –20°C to –80°C.

Store diluted material at –20°C to

–80°C. Avoid multiple freeze /

thaw cycles.

References/ Clinical Studies Handling Instructions

• Motta MR, Castellani S, Rizzi S, Curti A,

Gubinelli F, Fogli M, Ferri E, Cellini C, Baccarani

M, Lemoli RM (2003) Generation of dendritic

cells from CD14+ monocytes positively selected

by immunomagnetic adsorption for multiple

myeloma patients enrolled in a clinical trial

of anti-idiotype vaccination.

British Journal of Hematology 121:240–250

• Schuler-Thurner B, Schultz E, Berger T, Weinlich

G, Ebner S, Woerl P, Bender A, Feuerstein

B, Fritsch P, Romani N, Schuler G. (2002)

Rapid induction of tumor- specific

type 1 T helper cells in metastatic

melanoma patients by vaccination with

mature, cryopreserved, peptide-loaded

monocyte-derived dendritic cells.

J Exp Med 195(10):1279–1288

• Mackensen A, Drager R, Schlesier M,

Mertelsmann R, Lindemann A (2000)

Presence of IgE antibodies to bovine

serum albumin in a patient developing

anaphylaxis after vaccination with human

peptide-pulsed dendritic cells. Cancer Immunol

Immunother 49:152–156

• Thurner B, Haendle I, Roder C, Dieckmann D,

Keikavoussi P, Jonuleit H, Bender A, Maczek C,

Schreiner D, von den Driesch P, Brocker EB,

Steinman RM, Enk A, Kampgen E, Schuler G

(1999) Vaccination with mage-3A1 peptidepulsed

mature, monocyte-derived dendritic cells

expands specific cytotoxic T cells and induces

regression of some metastases in advanced

stage IV melanoma. J Exp Med 190:1669–1678

• Dhodapkar MV, Steinman RM, Sapp M, Desai H,

Fossella C, Krasovsky J, Donahoe SM, Dunbar

PR, Cerundolo V, Nixon DF, Bhardwaj N (1999)

Rapid generation of broad T-cell immunity in

humans after a single injection of mature

dendritic cells. J Clin Invest 104:173–180

Price
EUR3.443
USD4.303
GBP2.758
DKK25.655
JPY566.581
PLZ11.738
SEK32.179
NOK27.328
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