Hematopoietic progenitor cell antigen CD34 0.1 mg Hematopoietic progenitor cell antigen CD34 0.05 mg

Source: Chicken

 Purity: Immunoaffinity Purified

 Clonality: Polyclonal

 Crossreactivity: Human

 Format: Phosphate-Buffered Saline. No preservatives added.

 Storage: 4 degree C for short term (weeks) and -20 degree C for long term. Avoid frequent freeze and thaw.

 Stability: 6-12 months at -20 degree C.

 Shipping: Products may be shipped on ice pack or dry ice. 
 
 CD34 ANTIBODY TARGET DESCRIPTION:
Synonym Names for CD34 antibody: CD34; CD34 antigen isoform b

Function: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

Subcellular Location: Membrane; single-pass type I membrane protein.

Tissue Specificity: Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.

Developmental Stage: On early hematopoietic progenitor cells.

Ptm: Highly glycosylated.

Ptm: Phosphorylated on serine residues by PKC.

Disease: Abnormal CD34 expression in leukemogenesis.

Similarity: Belongs to the CD34 family.

Summary: CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells.[supplied by OMIM].

Hematopoietic progenitor cell antigen CD34 reacts with human.

OMIM: 142230; gene. [NCBI / EBI]

Pathways:
KEGG pathway: Cell adhesion molecules (CAMs) 04514
KEGG pathway: Hematopoietic cell lineage 04640

Products similar to CD34 antibody:
 IgG
    CD34 [4H11[APG]] antibody (FITC), IgG
    CD34 [MEC14.7] antibody, IgG
    CD34 [MEC14.7] antibody (RPE), IgG
    CD34 [4H11(APG)] antibody (APC), IgG
    CD34 [B458 (ICO-115)] antibody, IgG
 
 
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